About
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer
The information in the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer relates
cytogenetic changes and their genomic consequences, in particular gene fusions, to tumor characteristics, based
either on individual cases or associations. All the data have been manually culled from the literature by Felix
Mitelman in collaboration with Bertil Johansson and Fredrik Mertens.
The Mitelman Database is supported by National Cancer Institute, the Swedish Cancer Society and the Swedish
Childhood Cancer Foundation. The database is updated quarterly in January, April, July, and October.
Citation of the Database
To cite the use of the Mitelman Database from this website in a publication, please quote the following:
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer (2024). Mitelman F, Johansson
B and Mertens F (Eds.), https://mitelmandatabase.isb-cgc.org
In addition, when using information about chromosomal gains and losses (found on the Karyotype
Info and Overall Chromosomal Imbalances pages), please also cite the following:
CytoConverter: a web-based tool to convert karyotypes to genomic coordinates. Wang, J., LaFramboise, T.
BMC
Bioinformatics 20, 467 (2019).
https://doi.org/10.1186/s12859-019-3062-4
Some genomic coordinates were obtained from the Matched
Annotation from NCBI and EMBL-EBI (MANE) project.
A joint NCBI and EMBL-EBI transcript set for clinical genomics and
research. Morales, J., Pujar, S., Loveland, J.E. et al. Nature 2022 Apr;604(7905):310-315. PubMed; PubMed
Central; DOI: 10.1038/s41586-022-04558-8
Mitelman Database
Database last updated on October 15, 2024
- Cytogenetic cases: 78,294
- Unique cytogenetic aberrations: 49,122
- Unique gene fusions: 34,096
- Genes involved: 14,078
Contact Us
For questions on the web site, please email at feedback@isb-cgc.org
For questions on interpretation of search results, please email at mitelman-info@isb-cgc.org
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer by Mitelman F, Johansson B and Mertens F is licensed under a Creative Commons Attribution 4.0 International License. |